Paris (France) and Boulder (CO, USA), May 16, 2023 – 8:30 am CEST – SpineGuard (FR0011464452 – ALSGD), an innovative company that deploys its DSG (Dynamic Surgical Guidance) sensing technology to secure and streamline the placement of bone implants, and XinRong Medical Group, a China leader in medical technology, announced today that they expanded their collaboration with the signature of three concomitant agreements: • China exclusive distribution extension to the whole SpineGuard product portfolio • Funding of the NMPA (National Medical Product Administration) registration process for SpineGuard new products via a cash injection of €500K by XinRong Medical in SpineGuard capital • Potential co-development of a Smart Screw system for the Chinese spinal surgery market Until today, XinRong Medical was only selling the SpineGuard’s Classic PediGuard products in China, this new distribution agreement will enable them to commercialize the Curved, the XS, the Canulated and the Threaded versions of SpineGuard’s DSG (Dynamic Surgical Guidance) spinal drilling probes. The NMPA registration of these new devices for the Chinese market will be funded via a €500K equity injection by XinRong Medical. SpineGuard will issue 500,000 new shares priced at €1.00 per share representing 1.28% of current issued shares with a 18-month lock-up period. SpineGuard will own all product registrations that will be executed through a third-party regulatory agent jointly appointed by both companies. XinRong Medical and SpineGuard also decided to envision the co-development of a DSG enabled single step pedicle screw system with three key milestones triggering payments: 1) evaluation of the registration process and market access path, 2) product design and submission of the registration dossier, and 3) product clearance. China’s spine market is the world’s second-largest market after the USA driven by an aging population, increasing disease prevalence and treatment rates, along with access to care growing affordability. Pierre Jérôme, Chairman, CEO and Co-founder of SpineGuard, said: “This three-pronged agreement is a significant step forward for SpineGuard and the deployment of our x-ray free real time sensing technology in China, the largest market for spinal surgical devices after the United States. With XinRong, we took the time to elaborate a common strategy and tailor our partnership based on our early collaborative experience introducing the original version of PediGuard in China. We now have a clear roadmap and dedicated funds to successfully market our smart drilling devices and secure spinal fusion procedures across Chinese provinces.” Christine Zhang, CEO of XinRong Medical, added: “I am thrilled about the three-pronged agreement between SpineGuard and XinRong. It is indeed a significant step forward for XinRong, and I commend the board, the company XinRong and SpineGuard team for taking the time to collaborate and develop a common strategy. The dedication to tailoring out partnership based on both sides’ early collaborative experience introducing the original version of PediGuard in China is a testament to SpineGuard commitment to providing innovative medical devices to the global medical community. The dedicated funds to market SpineGuard x-ray free real time guidance technology across Chinese provinces is a great opportunity to expand SpineGuard's presence in the Chinese market. I am confident that this innovative technology will provide more precise and safer spinal surgery for Chinese patients. Once again, I greet this milestone achievement, and I look forward to seeing the continued success of SpineGuard and XinRong.”  About SpineGuard® Founded in 2009 in France and the USA by Pierre Jérôme and Stéphane Bette, SpineGuard is an innovative company deploying its proprietary radiation-free real time sensing technology DSG® (Dynamic Surgical Guidance) to secure and streamline the placement of implants in the skeleton. SpineGuard designs, develops and markets medical devices that have been used in over 95,000 surgical procedures worldwide. Twenty-four studies published in peer-reviewed scientific journals have demonstrated the multiple benefits DSG® offers to patients, surgeons, surgical staff and hospitals. Building on these strong fundamentals and several strategic partnerships, SpineGuard has expanded the scope of its DSG® technology in innovative applications such as the « smart » pedicle screw, the DSG Connect visualization and registration interface, dental implantology and surgical robotics. DSG® was co-invented by Maurice Bourlion, Ph.D., Ciaran Bolger, M.D., Ph.D., and Alain Vanquaethem, Biomedical Engineer. SpineGuard has engaged in multiple ESG initiatives. For further information, visit www.spineguard.com About XinRong Medical XinRong Medical, a China leader in medical technology, is dedicated to increasing patient affordability and providing the most advanced solution for surgeons such that they can deliver the best patient care. XinRong Medical offers innovative solutions in orthopaedic surgery, neurosurgery, and reconstructive surgery. XinRong Medical is a professional orthopaedic implants manufacturing enterprise invested by the world’s leading investment institution The Black Stone Group, (NYSE: BX). It has constantly innovated and moved forward to new materials, new techniques and minimally invasive therapy field. Established in 2000, XinRong Medical was one of the first companies in China cleared by SFDA to manufacture orthopaedic implants. For additional information, visit www.XRBest.Com. Disclaimer The SpineGuard securities may not be offered or sold in the United States as they have not been and will not be registered under the Securities Act or any United States state securities laws, and SpineGuard does not intend to make a public offer of its securities in the United States. This is an announcement and not a prospectus, and the information contained herein does and shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of the securities referred to herein in the United States in which such offer, solicitation or sale would be unlawful prior to registration or exemption from registration.

XinRong Medical has recently appointed Mr. Stephen Ooi as a member of the board of directors.

PARIS and SAN FRANCISCO, June [XX]th, 2017 – 18:00 CET – SpineGuard (FR0011464452 – ALSGD), an innovative company that develops and markets disposable medical devices designed to make spine surgery safer, announced today an exclusive distribution agreement with XinRong Medical Group for selling and marketing PediGuard® in China, Hong Kong and Macau. The ChineseChina’s spine market has become the world’s second-largest market in spine after the USA and is expected to be worth over US$1 billion by 2019 , driven by an ageing population, increasing disease prevalence, improving treatment rate, and growing affordability. “We are thrilled by this agreement and I believe XinRong Medical Group has the right attributes to successfully introduce PediGuard in China where the number of spine fusions is growing rapidly creating a substantial need for a simple smart device consistently securing the placement of pedicle screws. Since its clearance by CFDA, numerous Chinese orthopedists and neurosurgeons expressed a strong interest for our DSG™ technology. We now very much look forward to seeing them adopt it in their spine surgery practice..,”, said Pierre Jérôme, CEO and co-founder of SpineGuard. “XR Medical is delighted to have partner with SpineGuard, the inventor of PediGuard and DSG™ technology. PediGuard is one of its kind in the market, and XinRongR Medical is very excited to introduce one of most advanced surgical solutions globally to the China market. SpineGuard’s cutting-edge technology allows surgical staff and patients to significantly reduce exposure to surgical radiation in the operating room (OR) and help surgeons achieve more precise spinal implantation in real time. “Ease of Use, Economy, Accuracy, and Safety” is what we want to bring surgeons in China, through which we could realize our vision of putting patients first. ”, added Christine Zhang, XinRong Medical Group’s CEO. Next financial press release: 2016 Half-year revenue: July 6, 2017 About SpineGuard® Founded in 2009 in France and the USA, by Pierre Jérôme and Stéphane Bette, SpineGuard’s mission is to make spine surgery safer by bringing real-time digital technology into the operating room. Its primary objective is to establish its proprietary DSG™ (Dynamic Surgical Guidance) technology as the global standard of surgical care, starting with safer screw placement in spine surgery and then in other surgeries. PediGuard®, the first device designed using DSG, was co-invented by Maurice Bourlion, Ph.D., Ciaran Bolger, M.D., Ph.D., and Alain Vanquaethem, Biomedical Engineer. It is the world’s first and only handheld device capable of alerting surgeons to potential pedicular or vertebral breaches. Over 50,000 surgical procedures have been performed worldwide with DSG™ enabled devices. Numerous studies published in peer-reviewed medical and scientific journals have demonstrated the multiple benefits that PediGuard® delivers to patients, surgical staff and hospitals. SpineGuard is expanding the scope of its DSG™ platform through strategic partnerships with innovative medical device companies and the development of smart instruments and implants. SpineGuard has offices in San Francisco and Paris. For further information, visit www.spineguard.com.

More than two thousand and one hundred years ago, Zhangqian visited to the western regions and got to know there was something which can travels thousand miles one day. It was said that the sweat before the neck part was in color. History recorded the Blood Horse as “travels thousands miles a day”, and named it also as “Dawan Horse”, “Tian Horse”. In order to get it, the emperor sent the army expedition to the western twice. At present, XINRONG also awarded the best salesman with the “excellent horse”- BMW.

In July, it’s our honor for XINRONG Academy to hold the third training course in training center of Orthopedics of Jishuitan. The content of “basic course of Orthopedics” is comprehensive, which contains the entire domain in Orthopedics, such as trauma, spine, adult joint, hand, sports medicine, children’s bone, bone tumors, orthopedic basic science and rehabilitation. There are many kinds of courses, which mainly develops by combining lectures, tutorship and discussion, and operation training. To improve the level of English while acquire professional knowledge, Bilingual is adopted among curriculum. Trainees who finish the “basic course of Orthopedics” can be awarded graduation certification of Orthopedics of Jishuitan, as well as obtaining 10 credits of national continuing-education.

There are profession courses which are mainly set for doctors of Spinal branch. Professors and teachers across the country have participated in this activity. During the 5-day training, trainees, trainers, and XINRONG Company absorbed a lot, which is also an honor to XINRONG Academy. After 5-day training, the fast-paced and pleasing training course of XINRONG and Orthopedics of Jishuitan ends at 17/06/2016. Our XINRONG also obtained many useful suggestions when communicated with other teachers and professors of Jishuitan. XINRONG MEDICAL, with diligent attitude, will devote ourselves to developing technical service, training education, and product innovation.

Recently, the government of JinFeng Town, Zhangjiagang City, has pronounced the 2014-2015 “the Most Caring Enterprise” prize. Based on the prominent performance and excellent repercussion, XINRONG MEDICAL has been awarded “the Most Caring Enterprise” prize again.

The 2013- 2015commendation conference of Jiangsu province for the credible medical equipment enterprises has been held at 27th, April in Nanjing. 一The director of SFDA, Mr. Hu Xiaoshu, the inspector, Mr. Fan Lesheng, the deputy director of inspection, Mr. Gong Shengjin, the Secretary General of medical device industry association, Mr. He Guozhu have participated the meeting.